Umucyo mumituku itukura kandi hafi-ya-infragre ya spekure yihutisha gukira muri selile zose.Bumwe mu buryo babigeraho ni ugukora nka antioxydants ikomeye.Barabuza kandi umusaruro wa nitric oxyde.
Urumuri rutukura kandi hafi-ya-infragre irashobora gukumira cyangwa guhindura kunanirwa kwumva?
Mu bushakashatsi bwakozwe mu mwaka wa 2016, abashakashatsi bakoresheje urumuri ruri hafi ya infragreire mu ngirabuzimafatizo zumva muri vitro mbere yo kubishyira mu myuka ya okiside mu kubangiza uburozi butandukanye.Nyuma y’ubushakashatsi bwakozwe mbere y’ubushakashatsi bw’ubumara bwa chimiotherapie na endotoxine, abashakashatsi bakoze ubushakashatsi basanze urumuri rwahinduye metabolism ya mitochondrial metabolisme hamwe n’ingutu ya okiside itera amasaha agera kuri 24 nyuma yo kuvurwa.
Abanditsi b'ubushakashatsi banditse bati: "Turatangaza ko igabanuka rya cytokine ikabije ndetse n'urwego rwo guhangayika bituruka kuri NIR ikoreshwa mu ngirabuzimafatizo za HEI-OC1 mbere yo kuvurwa na gentamicin cyangwa lipopolysaccharide".
Ibyavuye mu bushakashatsi byagaragaje ko mbere yo kuvurwa hifashishijwe urumuri ruri hafi ya infragre yagabanije ibimenyetso byerekana umuriro ujyanye no kwiyongera kw amoko ya ogisijeni ikora na aside nitide.
Kwiga # 1: Itara ritukura rishobora guhindura igihombo cyo kumva?
Hasuzumwe ingaruka z'urumuri ruri hafi ya infragreire yo kutumva nyuma yuburozi bwa chimiotherapie.Kumva byasuzumwe nyuma yubuyobozi bwa gentamicin na nyuma yiminsi 10 yo kuvura urumuri.
Kubisikana amashusho ya microscopique electron, "LLLT yongereye cyane umubare wimisatsi yimisatsi hagati no hagati.Kumva byatejwe imbere cyane na laser irrasiyo.Nyuma yo kuvurwa LLLT, ibipimo byo kumva no kubara imisatsi-selile byateye imbere ku buryo bugaragara. ”
Kwiga # 2: Itara ritukura rishobora guhindura igihombo cyo kumva?
Muri ubu bushakashatsi, imbeba zagaragayeho urusaku rukomeye mu matwi yombi.Nyuma yaho, ugutwi kwabo kwi buryo kwamurikiwe n’umucyo hafi ya-infragre yo kuvura iminota 30 buri munsi iminsi 5.
Gupima ibisubizo byubwonko bwubwonko bwerekanye ko gukira byihuse imikorere yumva mumatsinda yavuwe na LLLT ugereranije nitsinda ritavura kumunsi wa 2, 4, 7 na 14 nyuma y urusaku.Ubushakashatsi bwakozwe na Morphologie bwerekanye kandi umubare munini wimisatsi yo hanze yo kubaho mumatsinda ya LLLT.
Mu gushakisha ibipimo byerekana imbaraga za okiside na apoptose mu ngirabuzimafatizo zitavuwe vs abashakashatsi basanze “Ubudahangarwa bukomeye bwagaragaye mu ngingo z’amatwi y’imbere y’itsinda ritavura, mu gihe ibyo bimenyetso byagabanutse mu itsinda rya LLLT kuri 165mW / cm (2) ubucucike. ”
Ati: "Ibyavuye mu bushakashatsi byerekana ko LLLT igira ingaruka za cytoprotective kurwanya NIHL binyuze mu kubuza imvugo ya iNOS na apoptose."
Inyigisho # 3: Itara ritukura rishobora guhindura igihombo cyo kumva?
Mu bushakashatsi bwakozwe mu mwaka wa 2012, imbeba icyenda zahuye n’urusaku rwinshi kandi hageragejwe ikoreshwa ry’urumuri ruri hafi ya infragreire ku gukira kwumva.Bukeye bwaho urusaku rwinshi, ugutwi kwi bumoso kwimbeba zavuwe n’umucyo utagira urumuri rw'iminota 60 mu minsi 12 ikurikiranye.Amatwi y'iburyo ntiyavuwe kandi yafatwaga nk'itsinda rishinzwe kugenzura.
Ati: “Nyuma ya irrasiyo ya 12, amajwi yo kumva yagabanutse cyane ku matwi y'ibumoso ugereranije n'amatwi y'iburyo.”Iyo ubonye ukoresheje microscope ya electron, umubare wimisatsi yumva mumatwi yavuwe wari munini cyane ugereranije namatwi atavuwe.
Ati: “Ibyavuye mu bushakashatsi byerekana ko imishwarara yo mu rwego rwo hasi itera imirasire yo kumva nyuma yo guhahamuka gukabije.”
Igihe cyo kohereza: Ugushyingo-21-2022